Life Sciences

One Partner for World-Class Medical Devices and Medicines

Swagelok supports medical device, pharmaceutical, biopharmaceutical, and biotechnology companies with fluid system products and services that promote safe, reliable performance in the most sanitary and sterile of production environments. We also offer leak-tight components and assemblies that are easy to install, disassemble for cleaning, and reassemble, without compromising quality. TopPic

By investing time and resources in early-stage R&D for concept medical devices and pharmaceuticals, we become a core resource on the path to your successful project outcome. Our collaborative sales and engineering process allow you to focus on the development of new technologies while remaining flexible and agile; our team works on designing and fabricating while your team can focus on running your business.

For more than seven decades, we have demonstrated our commitment to designing, manufacturing, and delivering reliable fluid system components. Today, customers are asking us to expand our offerings and find new ways to help them solve emerging challenges.

Our specialists can help you manage the pressures that come with building the devices and manufacturing the medicines that support human wellness, including:

  • Providing design and assembly services tailored to your business to help get your medical device or pharmaceutical drug to market quickly
  • Maintaining a high degree of accuracy and purity throughout manufacturing processes and clinical procedures to ensure optimal results
  • Navigating a complex range of fluid system components and industry compliance standards, such as ISO 9001, 13485, and 14971
  • Improving operational efficiency and reducing costs despite demanding lead times and mounting logistics challenges related to products and materials

We connect manufacturers to components and assemblies that help their machines and equipment operate dependably. The team at Swagelok Minnesota | North Dakota | Appleton is the place to start for products and technical advice.

We Can Help You Exceed Your Time to Market Expectations

If you have a concept for a fluid system design, we can work with you to get your design from a concept and desired functionality to a ready-to-use prototype. This process includes:

  • Reviewing your application needs
  • Evaluating feasibility with instrumentation
  • Providing design recommendations on a P&ID

If you have a working prototype, we can review your fluid system design and work with you on enhancements and manufacturing feasibility. This process includes: 

  • Reviewing the prototype's functionality
  • Recommending system improvements for long-term feasibility and manufacturability
  • Reducing leak points and overall footprint
  • Safety improvements
  • Component selection

After working together to improve your prototype, our Swagelok-trained technicians can save you time by designing, assembling, and fabricating your fluid system assemblies.

Find out more by accessing our free life sciences solutions brochure



Swagelok Minnesota | North Dakota | Appleton supports the life sciences market in the design and manufacturing of:

  • Medical devices such as respirators and water purifiers
  • Pharmaceuticals
  • Biopharmaceuticals
  • Biotechnologies
  • Cosmetics
  • Gas delivery and control systems within health care facilities and research laboratories
  • Healthcare equipment for critical heart and brain surgeries


All our standard products and custom components are backed by the Swagelok Limited Lifetime Warranty. Everything we design, manufacture, and build is to help you achieve the highest level of application, process, and instrumentation integrity, as we know how important that is for those in the business of medical device and pharmaceutical drug manufacturing.


The remarkable dependability of Swagelok® tube fittings has been proven over 75 years. A leak-tight, gas-tight seal in an easy-to-install, easy-to-disassemble, and easy-to-reassemble form supports safe and reliable machine operations day after day. Find standard and specialty tube fittings and adapters in many alloys and configurations.

Gas Distribution Systems

We can design and assemble a gas delivery system for your manufacturing plant, clinic, or lab. Our standard gas delivery panels come fully assembled and tested. All systems are highly configurable with features and modifications to suit your specific system requirements.

Orbital Welding System

For consistent, efficient welds, the Swagelok® orbital welding system offers precision, control, portability, and touchscreen control. Make quality repeatable orbital gas tungsten arc welds (GTAW) for tubing and pipe. Real-time monitoring and recording streamline documentation for adherence to industry requirements.

Pressure Gauges

Choose from a wide selection of gauges designed for all conditions, ranging from low pressure to severe service. Multiple-mount configurations make our gauges convenient to install. Also, find other measurement devices including pressure transducersflow sensors, and thermometers.

Quick Connects

We offer a variety of quick-connect fittings that enable fast, simple operation without twisting, turning, or wrenching. These fittings are engineered to minimize spillage and air inclusion so you can make connections with confidence each and every time. 


Get the set of capabilities you need from your regulators. Swagelok pressure-reducing, back-pressure, and specialty regulators maintain pressure and minimize droop over a wide range of pressures and flows. Let our team help you by recommending and assembling regulator configurations.

Sanitary Hose

Get sanitary hose that meets specifications for clean room environments and other hygienic applications. Highly flexible, smooth-bore PFA core hose complies with FDA regulation 21CFR Part 177.1550, USP 87, 88 Class VI, and 3-A. PTFE core hose smooth bore provides chemical compatibility, drainability, and flexibility and is FDA and USP Class VI compliant. Industry standard end connections as well as custom connections and hose lengths are available.

Small-Bore Tubing

We have the small-bore tubing to form the backbone of your fluid delivery system. Compared to conventional piping, small-bore tubing (up to 2 in. [51 mm] O.D.) reduces the number of connections, and thus potential leak points, for greater system integrity.


Our process and instrumentation valves provide reliability and require low maintenance. Swagelok® ball valves are known for their durability and ability to suit a wide range of system conditions in the life sciences and manufacturing sectors. We also carry a variety of other valve options, like check valves, needle and metering valves, relief valves, and plug valves.


Our customers need leak-tight solutions, continuous quality, on-time delivery, as well as safe and reliable gas distribution. The field engineers at Swagelok Minnesota | North Dakota | Appleton's help create consistent and predictable results for manufacturing and research facilities, from determining needs to training staff to identifying the root cause of problems.

Design and Assembly

As health care equipment and medical devices become more compact and as laboratory applications demand higher-pressure components, we can support your R&D, prototyping, and final design approval stages, so you can focus on the manufacturing environment.

Essentials Training

Meet day-to-day challenges with certified training courses that include essential knowledge about tube fittings, tube bending, and hose management. We can also provide instruction on valve selection and regulator use. Ask our team about onsite and virtual opportunities.

Gas Distribution Program

Standardized, configurable, and documented gas distribution systems can improve process accuracy, repeatability, and uptime while making operator safety the focus. Our gas delivery and pressure control advisory services work together to help facilities operate safely and efficiently.

Hose Advisory Services

Eliminate a variety of hose-related issues that cause safety concerns or costly downtime. We will walk your facilities to learn what an optimized fluid system means to your ability to stay productive and profitable. Receive a detailed report containing overall findings and prioritized improvement recommendations.

Locally Stocked Inventory

Swagelok Minnesota | North Dakota | Appleton can assist you with inventory optimizing, organizing, labeling, and reordering to help prevent stockouts and reduce the risk of downtime. Eliminate transaction fees and avoid being bogged down by surplus items with carefully managed onsite inventory services.

Orbital Welding Training

Orbital welding training for your staff can help you overcome issues related to widespread welder shortages and communal knowledge loss. Make the most of what modern orbital welding offers with our five-day training course that enables attendees to set up, operate, troubleshoot equipment, and critique welds.


Email us or call 800-422-6410